Panthenol is an alcohol form of pantothenic acid, a vitamin B complex that is often referred to as vitamin B5 or pro-vitamin B5. Substance Name: Panthenol [USAN:USP:INN:BAN:JAN] RN: 16485-10-2 UNII: WV9CM0O67Z InChIKey: SNPLKNRPJHDVJA-UHFFFAOYSA-N Note The alcohol of pantothenic acid. One study found that applying panthenol to the nail can help hydrate the nail and prevent breakage. D-Pantothenic acid plays a key role in human intermediary metabolism. Description: D-Panthenol is a lipid-soluble compound manufactured through chemical synthesis. ChemSpider ID 115991. [3,4], Panthenol is an emollient that makes products smoother and more spreadable. How Your Hair Changes As You Age, Plus What to Do About It, The 19 Best Organic Exfoliators for Sensitive Skin, 17 Best Natural Makeup Products, Benefits, and Shopping Tips for 2022, The Truth about Non-Toxic Nail Polish, Plus the Best Alternative for Put-Together Nails, little cuts or sores like bug bites or shaving irritation. You very likely have pantothenic acid in your system right now, since it occurs in so many common food sources. Products containing panthenol can also help soothe and protect infants against irritant diaper dermatitis. Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol is an analogue of vitamin B5, and it would be oxidized to vitamin B5 in organisms. Dexpanthenol CID 4678. [2] Panthenol is used in thousands of personal care and cosmetic products, including baby lotion, bath products, eye makeup, fragrances, hair care products, nail care products, suntan lotion and other items. Panthenol takes the form of either a white powder or a transparent oil at room temperature. 81-13-. [4] It is also used in the biosynthesis of coenzyme A, which plays a role in a wide range of enzymatic reactions and in cell growth.[2][3]. : 201-327-3. Allantoin is a naturally-occurring compound that has anti-irritant, protective benefits for the skin. [12,13,14,15,16,17,18], Pantothenic acid exists in all living cells and tissues. If you looked around your home, youd likely run across panthenol in several ingredients lists of products you own. Molecular Weight: 205.25. The molar mass of this compound is 205.25 g/mol. Pantothenic acid is found in all living things. You might find it in your shine and strengthening nail treatments, or in hand creams and cuticle oils. C 18 H 21 NO 3 - codeine, a painkilling drug. (2021). Every purchase helps us donate to families in need & supports local artists. Sunblock spf gold oil drop. [2] 3, Further explanation. 582.5580 D-Pantothenyl alcohol. Panthenol if applied to the hairs can repair damage to the hair shaft, can smoothe the cuticles of the hair shaft and thus reduce split ends. A novel cosmetic approach to treat thinning hair. (2017). Molecular formula: C 9 H 19 NO 4 Molecular weight: 205.25 g/mol IUPAC name: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide . It is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100),[5] in propylene glycol, and slightly soluble in glycerin. Panthenols moisturizing properties also contribute to its anti-inflammatory nature. A 2019 study adds that panthenol may alleviate facial redness resulting from winter xerosis in people with sensitive skin. Chemical Formula: C9H19NO4. Another study 2 conducted in 2016 showed that panthenol interacts with lipids (ceramides and cholesterol) and proteins (keratin) in dry skin to improve hydration and elasticity. Manufactured by: China manufacturer. Vitamin B5 helps break down proteins, fats and carbohydrates from the food we eat. Human repeated insult patch testing of a cream containing 0.5 percent Panthenol. Pantothenic acid. Also called pantothenol, used as moisturizer and to improve wound healing in pharmaceutical and cosmetic products. [2][3], Panthenol readily penetrates into the skin and mucous membranes (including the intestinal mucosa), where it is quickly oxidized to pantothenic acid. Sec. D-Panthenol MSDS 1. DL-Panthenol: Chemical Name: 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide: Category: Impurity Standards : Product Stock Status: In-Stock : Pack Size Number . In a living cell, panthenol is converted to pantothenic acid, which then becomes an important part of the compound "Coenzyme A", which is important in cellular metabolism. Panthenol is a common ingredient present in a wide variety of products, including skin care products, due to its moisturizing, soothing, and anti-inflammatory properties. 8 (927) 113-38-58 8 (919) 824-30-75 8 (987) 820-05-94. info@decidesaratov.ru. ru en. . The conventional manufacturing process of panthenol involves chemical condensation of synthetic R-pantolactone (-hydroxy-,-dimethyl--butyrolactone) with 3-aminopropanol. Glossary of skin care ingredients. (1983). Panthenol is a pharmaceutical product that is used in various skincare products. 81-13-. Learn about its many uses. Longchang Chemical is a leading manufacturer and supplier of D-PANTHENOL in China. The headquartered located in the beautiful Spring city Jinan. Panthenol comes in two enantiomers: D, and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. Experts deem panthenol safe for personal care, cosmetic, and skin care use and suggest that it presents a low risk of side effects for consumers. It easily penetrates the skin retaining water and is a humectant, emollient and moisturizer. What is the difference between skin hydration and moisture? [1] Panthenol comes in two forms: D-panthenol, which is an oily substance, and DL-panthenol, which is a white powder. And its listed as likely safe for topical use by children. PubChem . Usage/Application: DL-Panthenol is the Provitamin of DL-Pantothenic acid (Vitamin B5), which plays a key role in the hu. CTFA Code No. Youre going to love our products so much that we guarantee it. Moreover, it enhances the skins permeability to active ingredients in topical products. Whether you're looking for powder, cream, or liquid mineral makeup, we've got you covered with eight recommended foundations. is supplier for DL-Panthenol. Studies and education in uni. Solubility: D-Panthenol is easy to dissolve in water, ethanol, methanol and propylene glycol. Panthenol is an alcohol derivative of pantothenic acid. Dexpanthenol (also known as pantothenol, D-panthenol or panthenol hereinafter) is a chemical compound which is one of the polyols, and amides. It is used as a moisturizer and humectant in cosmetics and personal care products. It appears as a highly viscous, colorless liquid. For those who hate stains, chemicals, and more stains. Get experts tips on caring for your hair in every stage of life. Panthenol is used in pharmaceutical and cosmetic products as a moisturizer and to improve wound healing. That said, most of the research now available on panthenol suggests that using a concentration 5 percent and under in a topical skin, hair, or nail product presents a very low risk to consumers. D- Panthenol is an analogue of pantothenic acid, a member of the B complex vitamins. Supplied by: China D-Panthenol manufacturer. Panthenol is known for its moisturising, soothing and repairing properties for both the skin and the hair. Panthenol, provitamin B5, chemical formula, skeletal structure. [10], [1] Oregon State University Linus Pauling Institute [2] Cosmeticsinfo.org [3] Personal Care Council [4] Personal Care Council [5] Cosmeticsinfo.org [6] Camargo, F.B., Gaspar, L.R., and Maia Campos, P.M., Skin moisturizing effects of panthenol-based formulations, Journal of Cosmetic Science (2011)Jul-Aug; 62(4):361-70 [7] Miller J.W., Rucker R.B. The connection has long been used medicinally as a topical agent in the treatment of diseases of the skin and mucous membranes, and cosmetically in medical skin care. We avoid using tertiary references. At room temperature, panthenol is typically a viscous, transparent oil or white powder. MDL number: MFCD00065006. [8,9] It dissolves in water. Product Name DL-Panthenol CAS 16485-10-2 Tel +86-513-85221310,83567255,83567156 Email post@chem-base.com This website collects cookies to deliver a better user experience. Buy Racemic Panthenol (CAS No- 16485-10-2) online from SimSon Pharma, a global manufacturer & supplier of pharmaceutical intermediates. Buy D-PANTHENOL in china. Topical therapeutic effects Panthenol has been used topically to treat wounds, bruises, scars, pressure and dermal ulcers, thermal burns, postoperative incisions/distention, and dermatoses. CAS Number: 16485-10-2. 239000008266 hair spray Substances 0.000 title abstract description 25; KPUWHANPEXNPJT-UHFFFAOYSA-N Disiloxane Chemical compound; spray . US7815925B1 - Hair spray formula and method - Google Patents . This includes a positive effect on the skin, which is why many manufacturers often include it in topical cosmetic products. Vector. . Shandong Lanhai Industry Co.,Ltd. In: Erdman JWJ, Macdonald IA, Zeisel SH, eds. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Read on to learn how to perform a patch test and identify potential chemical. The carbon atoms in the chemical structure of D-Panthenol are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated - each carbon atom is considered to be associated with enough hydrogen atoms to provide the . We use natural & safe ingredients to make wonderfully effective products. Contact Now. Available for both RF and RM licensing. In topical cosmetics, product manufacturers often use panthenol as a moisturizer. SUBSTANCE IDENTIFICATION 1.1. In rare cases, skin irritation and contact allergies have been reported. Stereochemistry Panthenol comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. Panthenol is an odourless, slightly bitter, highly viscous, transparent, and colourless liquid at room temperature,[5] but salts of pantothenic acid (for example sodium pantothenate) are powders that are typically white. Panthenol (Panthenol) is a vitamin B5 derivative, commonly referred to as "pre-vitamin B5". One study found that panthenol may help slow down and hide the look of thinning hair. For cosmetic use, panthenol comes either in D form, or as a racemicmixture of D and L (DL-panthenol). It also helps your skin build up a barrier against irritation and water loss. (2018). Panthenol is a chemical substance which is derived from Vitamin B5 or Pantothenic Acid. Chemical raw materials for industrial production. So, it follows that panthenol can strengthen your finger- and toenails. D-Panthenol Care, formally known as D-Panthenol USP - Panthenol is an active ingredient for sophisticated cosmetic skin care and hair care products. A chemical formula describes a substance, down to the exact atoms which make it up. Panthenol's expanded chemical formula is HO-CH 2 -C (CH 3) 2 -CH (OH)-CONH-CH 2 CH 2 CH 2 -OH. CTFA Code No. Soluble In: Polypropylene glycol, Water, Chloroform. Pack Sizes: 10g, 50g, 100g, 250g, 500g. The Facts. 1 139-162 [14] CTFA. It's used as an. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Four-day minicumulative human skin irritation study with a product containing 0.5 percent Panthenol. National Center for Biotechnology Information, European Commission on Cosmetic Ingredients, eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32006D0257&from=EN, pubchem.ncbi.nlm.nih.gov/compound/DL-Panthenol, medlineplus.gov/druginfo/natural/853.html, cir-safety.org/sites/default/files/PANTS012017.pdf, accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=582.5580&SearchTerm=pantothenyl%20alcohol, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, The Water-Soluble Vitamins: C and B Complex. CAS No. It occurs organically and can also be produced from both plant and animal sources. Get 10 product recommendations and learn what to look for. UNII: 6777U11MKT Molecular Weight 222.5068 All Links to Resources Names & Synonyms Registry Numbers Structure Descriptors Links to Resources NLM Resources (File Locators) DrugPortal PubChem Other Resources (Internet Locators) eChemPortal EPA CompTox FDA SRS Names and Synonyms Name of Substance Methicone (20 CST) Synonyms Kf 99 UNII-6777U11MKT (2017). Min. Read on to find out why panthenol is in so many cosmetics and read the facts to understand how it affects your body. ChemicalCAS.com offers price quotation and technology support of chemical from China. (2011). D-Panthenol. Ubiquinol has many functions and is often added to shampoos and conditioners. FREE SHIPPING on orders above $55 | ALL Subscriptions ship FREE! Uses Experts do not associate any significant risks with the use of panthenol. Sodium is a Group IA alkali metal Atomic no. There are nine water-soluble vitamins in the human diet. CAS NO. [2] It improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing. [5] Studies show that formulations containing panthenol significantly decrease water loss through the skin and accelerate wound healing. Chronically dry or chapped lips stand no chance against these 20 moisturizing lip balms. This derivative is widely used in the beauty industry. 3-8-4 [16] Leo Winter Associates, Inc. (1974). Pantothenic acid is vitamin B5. The term pantothenic comes from the Greek word pantothen, which means everywhere. This refers to the fact that pantothenic acid is abundant and can come from both plant and animal sources. Its used to help hydrate and smooth your skin and hair from the inside in its ingestible form and from the outside in its topical form. Blackboard with the chemical formula of panthenol - download this royalty free Stock Illustration in seconds. 1.3. D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. CTFA Code No. CTFA Code No. Min. 3-8-23. [3] For this purpose, it is sometimes combined with allantoin. Molecular Formula CHNO. It is structurally similar to vitamin B5 except that it contains a hydroxyl group, making it an alcohol. Panthenol is a common ingredient in a host of products, including: In general, people tolerate panthenol well. Four-day minicumulative human skin irritation study with a product containing 0.5 percent Panthenol. EINECS No. Pantothenic acid. Panthenol is present in a wide variety of hair care products, with some evidence suggesting it may help prevent hair loss. Panthenol comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. But there isnt enough evidence to be sure, so the FDA suggests that more research is needed. Both the U.S. Food and Drug Administration (FDA) and the European Commission on Cosmetic Ingredients have approved panthenol for use in cosmetics. Ames: Wiley-Blackwell; 2012:375-390, Ferrandez, A. et al. The 2D chemical structure image of DL-Panthenol is also called skeletal formula, which is the standard notation for organic molecules. Grades: Highly Purified. We use panthenol more often than we think, as it is a common ingredient in various creams, mascaras, and serums. The 2D chemical structure image of D-Panthenol is also called skeletal formula, which is the standard notation for organic molecules. Panthenol (pantothenol) is an alcohol form of the B5 vitamin pantothenic acid. Stickers and wall decals of Panthenol, provitamin B5, chemical formula, skeletal structure. The risk of having skin irritation from personal care products with panthenol is low, possibly because of the low levels of panthenol in these products. This review board found no significant evidence that cosmetic products containing panthenol irritate or otherwise harm the skin, except in case of allergy. It coats the hair and seals its surface,[citation needed] lubricating the hair shaft and giving it a shiny appearance. Chemical Name: D-PANTHENOL CAS No. Neither the Environmental Working Group nor the CIR classifies panthenol as potentially toxic or harmful. (2007). Keep reading for what clean, natural exfoliators are best for sensitive skin. It is a common ingredient in a wide array of skin care and personal care products due to its moisturizing, soothing, and anti-inflammatory properties. D- Panthenol is the biologically active enantiomer of Panthenol. Nitric acid; Orthophosphoric acid; Citric acid monohydrate; Panthenol is known to be the precursor of Vitamin B5 or . Hair care products include panthenol because of its ability to improve your hairs: It can also help protect your hair from styling or environmental damage by locking in moisture. It is also a moisturizer that helps keep the skin soft and conditioned. It binds to the hair shaft readily, so, it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.11%). Molecular weight: 205.25; 1.5. It features TILAMAR Boost 150, TILAMAR Fix A1000, D-Biotin, PENTAVITIN and Ethyl Panthenol. This helps hydrate the outermost layer of the skin and locks in moisture. * Free shipping on orders $55 and over valid to all 50 states and Puerto Rico. Keeping the skin moisturized can help prevent it from becoming sensitive and easily irritated. 16485-10-2 D,L-Panthenol, aka Pro-Vitamin B5, is a stable racemic mixture of D-Panthenol and L-Panthenol. A person concerned about potential irritation can do a patch test before applying a product containing panthenol to their face or body. EINECS #: 201-327-3 1.7. CTFA Code No. It is a stable, water-soluble, light ingredient that readily penetrates the skin. Unlike vitamin E or vitamin K, which occurs in several chemically related forms known as vitamers, pantothenic acid is only one chemical compound.It is a starting compound in the synthesis of coenzyme A (CoA . D-Panthenol adds nourishment and moisturization to your skin and makes your skin soft, supple and plump, decreasing fine lines and wrinkles. Ames: Wiley-Blackwell; 2012:375-390 [8] Personal Care Council [9] National Institutes of Health [10] Ferrandez, A. et al. All rights reserved. (n.d.). In the quotation from China factory supplier, we will include price . 3-8-12 [17] CTFA. Panthenol is also occasionally used in makeup products as well. Storage Condition: The product may be stored for 24 months from the date of manufacture in the unopened original contai NO: 81-13- Molecular Formula: C9H19NO4 Molecular Weight: 205.25 g/mol. Formulation Guide CAS No. Although its widely considered beneficial as a supplement, its only classified as likely safe for topical use on the skin, hair, and nails. We avoid using tertiary references. Dexpanthenol | C9H19NO4 - PubChem National Library of Medicine National Center for Biotechnology Information About Posts Submit Contact Search PubChem Apologies, we are having some trouble retrieving data from our servers. Also, both organizations note that panthenol is not: However, a person can still have an allergic reaction to panthenol. Chemical Name: Dexpanthenol IUPAC NAME: 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide CAS No. (1983). "Process for the production of panthenol" [11] Whole Foods Market [12] Personal Care Council [13] Final Report on the Safety Assessment of Panthenol and Pantothenic Acid, International Journal of Toxicology, January/February 1987 vol. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. That means theres no significant evidence that panthenol causes harm, and plenty of anecdotal evidence that its helpful for many skin concerns. It also has anti-inflammatory properties and is involved in activating the proliferation of cells that are important for wound healing and restoring the function of the skin barrier. It is also known as panthothenic acid and has therapeutic qualities. In ointments it is used for the treatment of sunburns, mild burns, minor skin injuries, and disorders (in concentrations of up to 25%). Panthenol Molecular Formula CHNO Average mass 205.251 Da Monoisotopic mass 205.131409 Da ChemSpider ID 4516 More details: Names Properties Searches Spectra Vendors Articles More Names and Synonyms Database ID (s) Validated by Experts, Validated by Users, Non-Validated, Removed by Users Panthenol [BAN] [INN] [JAN] [USAN] [USP] [Wiki] Panthenol is the alcohol analog of vitamin B5 and is a very versatile ingredient that is often overlooked by skincare specialists and consumers alike. Chemical Formula: Synonyms Vitamin B5 Description Panthenol is the alcohol form of pantothenic acid, more familiar as Vitamin B5. The National Institutes of Health (NIH) classifies panthenol as possibly safe for general topical applications and nasal sprays. Pantothenic acid is extremely hygroscopic. Business listings of D Panthenol manufacturers, suppliers and exporters in Mumbai, , , Maharashtra along with their contact details & address. Panthenol's expanded chemical formula is HOCH2C(CH3)2CH(OH)CONHCH2CH2CH2OH.
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